Medicine

Progressing ASO therapies from growth to execution

.Completing interests.R.S., M.S., H.G. as well as A.A.R. are coordinators of the 1M1M project. H.G. and A.A.R. are board of supervisors participants and also R.S., M.S. and A.A.R. are participants of the scientific advising board of N1C. A.A.R. divulges employment through LUMC, which has patents on exon-skipping modern technology, several of which has actually been actually licensed to BioMarin and consequently sublicensed to Sarepta. As co-inventor of a few of these patents, A.A.R. was actually allowed to a portion of aristocracies. A.A.R. further reveals functioning as ad hoc expert for PTC Therapeutics, Sarepta Therapeutics, Regenxbio, Dyne Therapies, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and Astra Zeneca. Over the last 5 years, A.A.R. additionally performed ad hoc consulting with for Alpha Anomeric. A.A.R. likewise mentions subscription of the medical boards of advisers of Eisai, Hybridize Therapies, Silence Rehabs, Sarepta Rehabs, Sapreme and Mitorx. Over the last 5 years, A.A.R. was actually additionally a scientific advisory board member for ProQR. Commission for A.A.R. u00e2 s consulting and also advising activities is actually paid to LUMC. Over the last 5 years, LUMC also got speaker gratuity from PTC Rehabs, Alnylam Netherlands, Italfarmaco and Pfizer as well as moneying for deal analysis coming from Sapreme, Eisai, Galapagos, Synaffix as well as Alpha Anomeric. Task backing is actually obtained from Sarepta Rehabs as well as Entrada using unrestricted gives. H.G. has nothing at all to reveal relative to the subject matters dealt with within this composition. In the past 5 years, he has also acquired consultancy honoraria coming from UCB. M.S. acquired working as a consultant honoraria from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and Solaxa over the last 5 years, all unconnected to the present composition. R.S. has nothing at all to make known in relation to the topics dealt with in this document. She has actually obtained audio speaker and/or working as a consultant gratuity or sponsoring payments coming from Abbvie, Bial, STADA and also Everpharma previously 5 years.

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